Stratify or adjust? Dealing with multiple populations when evaluating rare variants
نویسندگان
چکیده
منابع مشابه
Stratify or adjust? Dealing with multiple populations when evaluating rare variants
The unrelated individuals sample from Genetic Analysis Workshop 17 consists of a small number of subjects from eight population samples and genetic data composed mostly of rare variants. We compare two simple approaches to collapsing rare variants within genes for their utility in identifying genes that affect phenotype. We also compare results from stratified analyses to those from a pooled an...
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ژورنال
عنوان ژورنال: BMC Proceedings
سال: 2011
ISSN: 1753-6561
DOI: 10.1186/1753-6561-5-s9-s101